Is it odd that I have mice with disrupted ovaries? In fact, I think I have two mouse lines that are subfertile. So yes, over time these animals lose the ability to produce eggs. Unfortunately, there aren't problems directly with the eggs. It is more the supporting cells that are disrupted. One probably has a disruption in the theca cells. The other line is less obvious, but possibly also in the theca cells. What I have found is that there is little federal funding for female infertility. Seriously, I would love to investigate these issues, but nobody cares.
Maybe if I were in Germany things would be different. They are worried that their population is actually decreasing. It seems as if people are waiting much longer to settle down and when they do they have few or no kids. This leads me to question whether they might have more concern over female aging and fertility. It seems that they might want to extend the fertile years to permit their population to grow and maybe there would be more federal funding. I haven't investigated this but am curious if this could be the case.